Related Experiment Video
Updated: Aug 6, 2026

07:26
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Signs and symptoms from ectodermal organs in young Swedish individuals with oligodontia
B Bergendal1, J Norderyd, M Bågesund
1National Oral Disability Centre, The Institute for Postgraduate Dental Education, Jönköping, Sweden. birgitta.bergendal@lj.se
International Journal of Paediatric Dentistry
|August 2, 2006
Summary
Oligodontia, a rare condition of missing teeth, often presents with other ectodermal symptoms like reduced salivary secretion. Early dental assessment can aid in identifying this condition, with a prevalence of 0.090%.
Area of Science:
- Dentistry
- Genetics
- Dermatology
Background:
- Oligodontia is a congenital condition characterized by the absence of six or more teeth.
- Individuals with oligodontia may exhibit signs and symptoms affecting other ectodermal structures.
Purpose of the Study:
- To assess signs and symptoms in other ectodermal organs in young individuals with oligodontia.
- To determine the prevalence of oligodontia in the studied population.
Main Methods:
- A clinical study involving children diagnosed with oligodontia.
- Examinations included structured interviews on ectodermal organ symptoms and salivary secretion tests.
Main Results:
- 123 individuals participated, with 75.9% exhibiting one to four additional ectodermal signs or symptoms.
- Low salivary secretion was the most common finding; 9.6% reported impaired sweat, hair, or nail function.
- The prevalence of oligodontia was found to be 0.090%.
Conclusions:
- Early identification of oligodontia is possible by monitoring permanent incisor eruption by age 8.
- Self-reported symptoms of ectodermal dysfunction have low validity, highlighting the need for standardized clinical diagnostic criteria.
Related Concept Videos
Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Oppositional Defiant Disorder
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
Assessment of the Mouth
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Notch Signaling Pathway
The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule.
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

