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Updated: Aug 6, 2026

Ablation of a Neuronal Population Using a Two-photon Laser and Its Assessment Using Calcium Imaging and Behavioral Recording in Zebrafish Larvae
Published on: June 2, 2018
Telencephalic ablation results in decreased startle response in goldfish
Lyndsey E Collins1, Robert F Waldeck
1Neuroscience Program, University of Scranton, Scranton, PA 18510, USA.
Abstract:
Our investigation concerns the connection between the telencephalon and the startle response, mediated by reticulospinal neurons. Before surgery fish respond to the startle stimulus in 95% of the trials and 66% of the time with complete full turns. Following telencephalon removal fish respond in only 50% of the trials but make complete full turns only 7% of the time. There is no significant change found in control fish. This suggests a modulatory role of the telencephalon in regards to startle behavior.

