Establishment of dorsal-ventral and terminal pattern in the Drosophila embryo

Dorsal-ventral and terminal pattern formation in the Drosophila embryo is mediated via inductive signals originating during oogenesis from the somatic follicle cells that ensheath the developing oocyte. This somatically expressed spatial information controls dorsal-ventral development by defining the polarity of a signal transduction pathway that results in the graded nuclear concentration of the dorsal gene product, a transcription factor.