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Related Experiment Videos

Rhinoentomophthoromycosis.

Mathew M Thomas1, Sumangala M Bai, Chitra Jayaprakash

  • 1Department of Dermatology, Dr. S. M. C. S. I. Medical College and Hospital, Karakonam, Trivandrum, Kerala, India. mathewtm_2000@yahoo.com

Indian Journal of Dermatology, Venereology and Leprology
|August 2, 2006
PubMed
Summary

Rhinoentomophthoromycosis, a fungal infection, was diagnosed in a patient with nasal swelling. Combination therapy with fluconazole and potassium iodide led to complete symptom resolution and CT-confirmed healing.

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Area of Science:

  • Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Subcutaneous zygomycosis is a rare fungal infection that can affect the nose.
  • Rhinoentomophthoromycosis is a specific type of subcutaneous zygomycosis caused by Conidiobolus coronatus.

Observation:

  • A 60-year-old patient presented with a year-long history of slowly progressive nasal swelling.
  • Clinical diagnosis suggested subcutaneous zygomycosis.
  • Tissue fungal culture confirmed Conidiobolus coronatus, leading to a diagnosis of rhinoentomophthoromycosis.

Findings:

  • The patient received a 5-month course of combination therapy: oral fluconazole and oral potassium iodide.
  • Complete resolution of nasal swelling and symptoms was observed.
  • Serial CT scans of the paranasal sinuses demonstrated gradual reduction of swelling, indicating treatment efficacy.

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Implications:

  • Early diagnosis and prompt combination therapy are crucial for successful management of rhinoentomophthoromycosis.
  • This case highlights the effectiveness of fluconazole and potassium iodide in treating this fungal infection.
  • This is the first reported case of rhinoentomophthoromycosis from Kerala, India, expanding the known geographical distribution of the disease.