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Updated: Aug 6, 2026
Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Osteopenia is common in adult male patients with active juvenile idiopathic arthritis
Parshant Aggarwal1, Amita Aggarwal, Sushil Gupta
1Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Objective:
To assess the prevalence of osteopenia in Southeast Asian men with active juvenile idiopathic arthritis (JIA) and to identify predictors of reduced bone mineral density (BMD).
Methods:
BMD of 30 men with active JIA and 23 healthy men was assessed by dual energy x-ray absorptiometry scans. Clinical variables that influence bone mass were also analyzed. T scores were calculated based on Caucasian normative data.
Results:
Absolute BMD (g/cm(2)) was significantly lower in men with active JIA compared to controls at all measured sites, i.e., lumbar spine (p = 0.018), hip (p = 0.018), and distal third of forearm (p = 0.044). More subjects in the JIA group had low BMD (T score
Conclusion:
A majority of Southeast Asian men with active JIA have reduced BMD. More patients in our cohort had low BMD compared to reports from Western countries. This finding may be attributed to use of Caucasian normative data, uncontrolled disease activity, severity of disease, poor nutritional status, or an ethnic variation.
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