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Related Experiment Videos

Ischemic scleroderma wounds successfully treated with hyperbaric oxygen therapy.

Y Michael Markus1, Mary J Bell, A Wayne Evans

  • 1Division of Rheumatology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Canada.

The Journal of Rheumatology
|August 2, 2006
PubMed
Summary
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Hyperbaric oxygen therapy (HBOT) effectively healed severe scleroderma ulcers in two patients. This innovative treatment offers a new option for managing these challenging chronic wounds.

Area of Science:

  • Dermatology
  • Vascular Medicine
  • Wound Healing

Background:

  • Hyperbaric oxygen therapy (HBOT) is established for refractory wounds, primarily those linked to arterial insufficiency.
  • Scleroderma often causes intractable ulcers due to local ischemia, posing significant treatment challenges.

Observation:

  • Two patients with scleroderma presented with severe, bilateral extremity ulcers.
  • Transcutaneous oximetry confirmed local ischemia as the underlying cause.

Findings:

  • Both patients received 30 HBOT sessions at 2.4 ATA.
  • Successful wound healing was achieved in both cases following HBOT.

Implications:

  • This study reports the first successful use of HBOT for scleroderma-related ulcers.

Related Experiment Videos

  • HBOT may be an unrecognized, effective treatment modality for difficult chronic scleroderma wounds.