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Updated: Jul 30, 2026

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Published on: March 11, 2016
[Ultrasound evaluation of intrahepatic hemodynamic disorders in patients with renal tuberculosis]
Abstract:
Seroechography, duplex, color, and energy Doppler studies were used to examine 50 patients with different forms of renal tuberculosis. The nature of renal blood flow was shown to depend on the magnitude of pathomorphological changes in tuberculous lesion. Spectral and energy Doppler studies revealed enhanced blood flow in the area of tuberculous infiltration. In all forms of nephrotuberculosis, there was an increase in peripheral vascular resistance, which was associated with vasoconstriction, obliteration, and diminished elasticity of vascular walls. Ultrasound angiography used in destructive forms of renal tuberculosis makes it possible to define treatment policy. The data of Doppler study were compared in relation to the glomerular filtration rate. The study ascertained that there was a reduction in glomerular filtration rates as the velocity characteristics of blood flow decreased and peripheral vascular resistance increased. The threshold values of renal hemodynamic parameters were determined to estimate renal filtration function. The reduction in end-diastolic blood flow velocity at different levels of the renal artery was of the greatest diagnostic informational value for diminished renal filtration function.
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