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Updated: Aug 6, 2026

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
Published on: February 23, 2020
Broca's area and the ventral premotor cortex in language: functional differentiation and specificity
1Department of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. angelafr@cbs.mpg.de
Abstract:
The idea is put forward that Broca's area (BA 44/45) and the left ventral premotor cortex (BA 6) together with the frontal operculum support different functions during language processing. While BA 44/45 is seen to be increasingly activated whenever the internal re-construction of a hierarchical structure from a sequential input is necessary, BA 6 is involved in the processing of local structural dependencies. This functional differentiation is discussed in the context of the neurocytoarchitectonical differentiation between agranular structure characterizing BA 6 and a dysgranular cortical structure characterizing BA 44/45. This differentiation is exemplified in the domain of language, but is possibly applicable to non-language domains.
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