Related Experiment Video
Updated: Aug 6, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Reversible posterior leukoencephalopathy caused by azathioprine in systemic lupus erythematosus
Chingching Foocharoen1, Somsak Tiamkao, Jiraporn Srinakarin
1Division of Allergy-Immunology-Rheumatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand. fching@kku.ac.th
Abstract:
The authors report a case of systemic lupus erythematosus with posterior leukoencephalopathy who presented with headache, tonic-clonic seizure, loss of consciousness and bilateral loss of vision, after taking azathioprine for three weeks. The patient had hypertension with normal eye grounds. The brain CT showed a hypodensity lesion at both bilateral occipital lobes, mainly in the white matter The symptoms and follow-up MRI were improved after the control of hypertension and discontinuation of azathioprine.
Related Concept Videos
Hepatic Encephalopathy
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
