Related Experiment Video

Updated: Aug 6, 2026

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
08:35

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice

Published on: March 17, 2015

Genetic predictors for acute experimental cold and heat pain sensitivity in humans

H Kim, D P Mittal, M J Iadarola

    Journal of Medical Genetics
    |August 3, 2006
    PubMed
    Abstract

    More Related Videos

    Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain05:10

    Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain

    Published on: August 30, 2022

    Determining heat and mechanical pain threshold in inflamed skin of human subjects13:21

    Determining heat and mechanical pain threshold in inflamed skin of human subjects

    Published on: January 14, 2009

    Related Concept Videos

    Thermosensation01:43

    Thermosensation

    Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
    Pain01:20

    Pain

    Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...