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The influence of variation in type and pattern of symptoms on assessment in pediatric asthma
Anne L Fuhlbrigge1, Theresa Guilbert, Joseph Spahn
1Channing Laboratory, Brigham and Women's Hospital, 181 Longwood Ave, Boston, Massachusetts 02115, USA. anne.fuhlbrigge@channing.harvard.edu
Insights
Most US children with asthma experience a moderate to severe symptom burden, despite perceived good control. Many children restrict activities, indicating that asthma treatment goals are not being met.
Area of Science:
- Pediatric Pulmonology
- Public Health
- Epidemiology
Background:
- Asthma is a significant chronic respiratory condition affecting children in the United States.
- Assessing the true burden of childhood asthma is crucial for effective management and public health initiatives.
Purpose of the Study:
- To conduct a national, population-based survey to examine the asthma-related health burden in US children.
- To evaluate the extent to which current asthma management aligns with established guidelines.
Main Methods:
- A 2004 telephone survey of children aged 4-18 with current asthma across the US.
- Data collection included symptoms, perceived control, activity limitations, healthcare use, and disease management.
- Asthma symptom burden was assessed using a global construct including short-term, long-term, and functional impact.
Main Results:
- While most children reported mild intermittent symptoms based on daytime occurrences, inclusion of nighttime symptoms reduced this classification.
- Using a global symptom burden construct, only 13% had mild intermittent disease; 62% had moderate/severe disease.
- Significant activity limitations were reported, with 47% avoiding exertion and 34% staying indoors to manage symptoms.
Conclusions:
- The majority of US children with asthma are not meeting the therapeutic goals set by the National Asthma Education and Prevention Program guidelines.
- Parents and children often overestimate asthma control, leading to potential underestimation of the disease burden.
- Common practice of restricting activities highlights deficiencies in asthma control and management strategies.
Objective:
We conducted a national, population-based survey to examine the asthma-related health burden of US children.
Methods:
A telephone-based survey was conducted in 2004 of children 4 to 18 years of age with current asthma in the United States. In 41,433 households screened, 1089 children reported current asthma; 801 interviews were completed by parents of children aged 4 to 15 years and by children themselves aged 16 to 18 years. The survey included questions about symptoms, perceived level of control, activity limitations, health care use, medicines, disease management, and knowledge. Global asthma symptom burden, derived from the National Asthma Education and Prevention Program guidelines, was composed of 3 components: short-term symptom burden (4-week recall), long-term symptom burden (past year), and functional impact (activity limitation).
Results:
The majority of children were classified with mild intermittent disease on the basis of recent daytime symptoms alone (80%); yet, when report of nighttime symptoms was included, the proportion of children classified as having mild intermittent symptoms decreased (74%). When asthma burden was assessed on the basis of the global symptom burden construct, only a minority (13%) of individuals was classified as having an asthma symptom burden consistent with mild intermittent disease; the majority (62%) was classified as having moderate/severe disease. In addition, the impact of asthma on the daily activities is substantial; avoiding exertion (47%) and staying inside (34%) are common approaches to improve control of asthma symptoms.
Conclusions:
The goals of therapy for asthma, based on the National Asthma Education and Prevention Program guidelines, have not been achieved for the majority of children. In addition, parents and children overestimate the child's asthma control and commonly restrict activities to control asthma symptoms. Deficiencies in the control of asthma may be related to the underestimation of the burden of disease.
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