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Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase
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The refolding of different alpha-fetoprotein variants

Susanna S J Leong1, Anton P J Middelberg

  • 1Centre for Biomolecular Engineering, The University of Queensland, St. Lucia, Australia. ssjl2@cam.ac.uk

Protein Science : a Publication of the Protein Society
|August 3, 2006
PubMed
Summary

Alpha-fetoprotein (AFP) foldability is independent of glycosylation, fatty acid binding, or refolding method. This study demonstrates AFP denaturation is reversible, refolding correctly in a redox-controlled environment.

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