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Chronic musculoskeletal pain in children: part II. Rheumatic causes
Jennifer L Junnila1, Victoria W Cartwright
1Army Medical Department Center and School, San Antonio, Texas, USA. Jennifer.Junnila@us.army.mil
Insights
Primary care physicians need to recognize childhood rheumatic diseases presenting as musculoskeletal pain. Early diagnosis and intervention, including ophthalmologist screenings for juvenile rheumatoid arthritis, are crucial for preventing long-term complications.
Area of Science:
- Pediatric Rheumatology
- Primary Care Medicine
- Musculoskeletal Disorders
Background:
- Rheumatic diseases in children often present with musculoskeletal pain, requiring primary care physician awareness.
- Juvenile rheumatoid arthritis can manifest with painless joint inflammation and normal rheumatologic tests, necessitating ophthalmologist screening for uveitis.
- Spondyloarthropathies, acute rheumatic fever, Henoch-Schönlein purpura, and systemic lupus erythematosus are other childhood rheumatic conditions with distinct presentations.
Purpose of the Study:
- To equip primary care physicians with knowledge of common pediatric rheumatic diseases.
- To highlight key diagnostic features and potential complications of these conditions.
- To guide appropriate initial management and referral strategies for suspected rheumatic illnesses in children.
Main Methods:
- Review of clinical presentations of various childhood rheumatic diseases.
- Discussion of characteristic symptoms, physical findings, and relevant laboratory/radiologic tests.
- Emphasis on early recognition and timely referral for definitive diagnosis and management.
Main Results:
- Juvenile rheumatoid arthritis may present with painless arthritis and uveitis, requiring ophthalmologic evaluation.
- Spondyloarthropathies are associated with enthesitis and often positive HLA-B27 tests.
- Acute rheumatic fever follows streptococcal infection, while Henoch-Schönlein purpura can present with arthritis preceding a rash.
Conclusions:
- Primary care physicians play a vital role in the early identification of pediatric rheumatic diseases.
- Judicious use of diagnostic testing and prompt referral are essential for optimal patient outcomes.
- Nonsteroidal anti-inflammatory drugs and physical therapy can be early therapeutic interventions.
Abstract:
Primary care physicians should have a working knowledge of rheumatic diseases of childhood that manifest primarily as musculoskeletal pain. Children with juvenile rheumatoid arthritis can present with painless joint inflammation and may have normal results on rheumatologic tests. Significant morbidity may result from associated painless uveitis, and children with juvenile rheumatoid arthritis should be screened by an ophthalmologist. The spondyloarthropathies (including juvenile ankylosing spondylitis and reactive arthritis) often cause enthesitis, and patients typically have positive results on a human leukocyte antigen B27 test and negative results on an antinuclear antibody test. Patients with acute rheumatic fever present with migratory arthritis two to three weeks after having untreated group A beta-hemolytic streptococcal pharyngitis. Henoch-Schbnlein purpura may manifest as arthritis before the classic purpuric rash appears. Systemic lupus erythematosus is rare in childhood but may cause significant morbidity and mortality if not treated early. Nonsteroidal anti-inflammatory drugs and physical therapy may be useful early interventions if a rheumatic illness is suspected. Family physicians should refer children when the diagnosis is in question or subspecialty treatment is required. Part I of this series discusses an approach to diagnosis with judicious use of laboratory and radiologic testing.
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