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Nourseothricin acetyltransferease: a positive selectable marker for Toxoplasma gondii

T Van Tam1, Peggy J Rooney, Laura J Knoll

  • 1Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, 53706, USA.

The Journal of Parasitology
|August 4, 2006
PubMed

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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...