Related Experiment Video
Updated: Aug 6, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Improved infant swallowing after gastroesophageal reflux disease treatment: a function of improved laryngeal
Dana L Suskind1, Dana M Thompson, Martha Gulati
1Section of Otolaryngology-Head and Neck Surgery, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA. dsuskind@surgery.bsd.uchicago.edu
Insights
Treating gastroesophageal reflux disease (GERD) in children significantly improved swallowing function and sensation. This suggests GERD control is vital for pediatric swallowing health.
Area of Science:
- Pediatric Gastroenterology
- Swallowing Disorders
- Neurology
Background:
- Gastroesophageal reflux disease (GERD) is common in infants and children.
- GERD can lead to significant feeding and swallowing difficulties, impacting growth and development.
- Dysphagia and aspiration are serious complications associated with GERD in pediatric populations.
Purpose of the Study:
- To investigate the impact of gastroesophageal reflux disease (GERD) treatment on pediatric swallowing function.
- To evaluate changes in laryngopharyngeal sensation and swallowing efficiency post-GERD intervention.
- To determine the relationship between GERD control and the resolution of pediatric swallowing dysfunction.
Main Methods:
- Retrospective chart and database review at two tertiary children's hospitals.
- Inclusion of pediatric patients (1-32 months) with diagnosed GERD and dysphagia (aspiration or pooling).
- Assessment of swallowing function and laryngopharyngeal sensation before and after medical or surgical GERD treatment.
Main Results:
- Significant improvements in both swallowing function and sensory testing were observed after GERD treatment.
- Children demonstrated enhanced ability to swallow and improved laryngeal sensation post-intervention.
- The study provides quantitative evidence of positive outcomes following GERD management.
Conclusions:
- Gastroesophageal reflux disease (GERD) can negatively affect laryngopharyngeal sensitivity, contributing to swallowing problems in children.
- Effective control of GERD through medical or surgical means can lead to notable improvements in pediatric swallowing.
- These findings highlight the clinical importance of addressing GERD to manage pediatric dysphagia, warranting further investigation.
Objective:
The objective of this study was to describe improvements in pediatric swallowing after gastroesophageal reflux treatment.
Study Design:
The authors conducted a retrospective database and chart review at two tertiary care children's hospitals.
Participants:
Patients (21 males, 7 females) ranged in age from 1 to 32 months. All patients had clinical evidence of gastroesophageal reflux disease (GERD) as well as evidence of dysphagia with aspiration (laryngeal vestibule and/or trachea) or hypopharyngeal pooling on flexible endoscopic evaluation of swallowing and sensation testing (FEESST) or videofluoroscopic swallow study (VSS).
Intervention:
Each child underwent either medical or surgical intervention for control of their GERD.
Outcome Measures:
Outcome measures were change in laryngopharyngeal sensation and swallowing function with repeat swallow evaluation after GERD treatment.
Results:
A significant improvement in both swallow function and sensory testing was demonstrated after GERD treatment.
Conclusions:
GERD may result in decreased laryngopharyngeal sensitivity, which may contribute to pediatric swallowing dysfunction. Control of GERD may improve swallow function. These findings have important clinical implications that need further study.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Esophageal Achalasia
Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
