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[Iris mammillations: three case reports].

W Kharrat1, P Dureau, C Edelson

  • 1Service d'Ophtalmo-Pédiatrie, Fondation Ophtalmologique Adolphe de Rothschild, 25-29 rue Manin, 75940 Paris cedex 19.

Journal Francais D'Ophtalmologie
|August 4, 2006
PubMed
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Iris mammillations are rare congenital iris abnormalities. While generally benign, they require regular monitoring due to potential complications like ocular hypertension and uveal melanoma, especially when associated with melanocytosis.

Area of Science:

  • Ophthalmology
  • Congenital Abnormalities
  • Genetics

Background:

  • Iris mammillations are congenital iris abnormalities presenting as vitiliform protuberances.
  • They can occur in isolation or alongside melanocytosis, increasing uveal melanoma risk.
  • Ocular hypertension is a potential complication.

Observation:

  • Three pediatric cases of iris mammillations are presented.
  • Findings included bilateral mammillations, papillary excavation, and unilateral mammillations with ocular melanocytosis.
  • Intraocular pressure remained normal in all cases during follow-up periods ranging from 13 to 22 months.

Findings:

  • Iris mammillations are congenital, often unilateral, and potentially hereditary.
  • Differential diagnoses include Lisch nodules and iris melanoma.

Related Experiment Videos

  • Associated melanocytosis poses a risk for uveal melanoma.

    • Implications:

    • Regular clinical follow-up is essential for patients with iris mammillations.
    • Monitoring is crucial for early detection of complications like ocular hypertension and uveal melanoma.
    • Understanding these lesions aids in managing potential risks in pediatric patients.