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Updated: Aug 6, 2026
05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
[Cavitary choroidal melanoma in a child]
H Faraj1, C Levy-Gabriel, L Lumbroso-Le Rouic
1Service d' Ophtalmologie, Institut Curie, Paris, France.
Journal Francais D'Ophtalmologie
|August 4, 2006
Summary
Cavitary melanoma, a rare form of uveal melanoma, can mimic benign cysts. This case highlights imaging and pathology for diagnosing this rare pediatric eye cancer.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
Background:
- Uveal melanoma is a rare ocular malignancy, exceptionally uncommon in pediatric patients.
- Intralesional cavities can develop within uveal melanoma, potentially mimicking benign intraocular cysts.
- Differentiating cavitary melanoma from cysts relies on identifying a solid base and thick cavity walls.
Observation:
- A 5-year-old girl presented with a large, pigmented intraocular mass in her left eye.
- Ocular ultrasonography, CT scan, and MRI revealed multiple hollow cavities within the mass.
- The clinical presentation suggested a potential diagnosis of cavitary melanoma.
Findings:
- The patient underwent enucleation for the intraocular mass.
- Pathological examination confirmed the diagnosis of choroidal melanoma.
- Fluorescence in situ hybridization (FISH) analysis showed no chromosomal 3 aberrations.
Implications:
- This case underscores the importance of advanced imaging in diagnosing rare pediatric uveal melanomas.
- Accurate differentiation between cavitary melanoma and benign cysts is crucial for appropriate management.
- Understanding the imaging characteristics of cavitary melanoma aids in early detection and treatment planning.
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