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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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[Tumors of the eyelids in the elderly]

J P Adenis1, A Sabatier, P-Y Robert

  • 1Service d'Ophtalmologie, CHU Dupuytren, 2, avenue Martin Luther King, 87042 Limoges CEDEX.

Journal Francais D'Ophtalmologie
|August 4, 2006
PubMed

Insights

Eyelid tumors vary widely, with benign types like papillomas being common. Malignant eyelid tumors require precise surgical removal using techniques like Mohs surgery, and sentinel lymph node biopsy is a promising tool for advanced cases.

Area of Science:

  • Ophthalmology
  • Dermatology
  • Surgical Oncology

Context:

  • Eyelid tumors present a diverse clinical spectrum.
  • Benign tumors (papillomas) and malignant neoplasms (carcinomas, melanomas) are frequently observed.
  • Accurate histopathologic margin assessment is crucial for managing malignant eyelid tumors.

Purpose:

  • To review the clinical presentation and management strategies for eyelid tumors.
  • To highlight histopathologic techniques for achieving clear surgical margins.
  • To discuss the role of sentinel lymph node biopsy in advanced malignant eyelid tumors.

Summary:

  • Common eyelid tumors include papillomas, basal cell carcinoma, squamous cell carcinoma, meibomian gland carcinoma, and melanomas.
  • Histopathologic techniques such as Mohs surgery, rapid fixation, and frozen sections are essential for margin control in malignant tumors.
  • Sentinel lymph node biopsy is a valuable but not yet fully validated tool for staging highly malignant tumors like melanoma and Merkel cell carcinoma.

Impact:

  • Improved understanding of eyelid tumor management.
  • Guidance on selecting appropriate histopathologic techniques for margin assessment.
  • Informed consideration of sentinel lymph node biopsy for advanced cases, pending further evidence.

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