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Updated: Aug 6, 2026
Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
Published on: November 30, 2016
[Characteristics of metastasis and recurrence following curative resection for colonic carcinoma]
Dong-bing Zhao1, Ji-dong Gao, Yi Shan
1Department of Abdominal Surgery, Cancer Hospital Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. dbzhao2003@sina.com
Objective:
To investigate the characteristics of metastasis and recurrence following curative resection for colonic carcinoma,and analyze the prognosis.
Methods:
The clinicopathological and follow-up data of 310 patients with colon carcinoma undergoing curative resection were analyzed retrospectively.
Results:
The recurrence rate after curative resection was 23.2% (72/310). The 5-year survival rate was 64.6%. Hepatic metastasis accounted for 38.9% of the cases. Gross classification,histological type, differentiation, lymph node metastasis were correlated with metastasis/recurrence. Univariate analysis revealed that gross classification, histological type, differentiation, lymph node metastasis, blood vessel invasion, TNM Stage, postoperative chemotherapy, portal chemotherapy were prognostic factors. Cox regression analysis revealed that only gross classification, lymph node metastasis, postoperative chemotherapy, portal chemotherapy were independent prognostic factors.
Conclusions:
Liver is the most common metastatic site after curative resection for colonic carcinoma. Gross classification, lymph node metastasis, postoperative chemotherapy, and portal chemotherapy are independent prognostic factors.
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