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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

Published on: March 12, 2015

[Identification of Toxoplasma gondii antigens recognized by specific T lymphocytes]

H Długońska1, K Dytnerska

  • 1Katedra Immunologii Uniwersytetu Lódzkiego.

Wiadomosci Parazytologiczne
|August 5, 2006
PubMed

Abstract:

The paper presents chosen experimental strategies for identifying of Toxoplasma gondii antigens recognized by specific T lymphocytes.

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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

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