[How to improve efficacy of onychomycosis treatment?]

R Nowicki1

  • 1Katedra i Klinika Chorób Skórnych i Wenerycznych AM w Gdańsku, 80-211 Gdańsk, ul Debinki 7.

Insights

Onychomycosis, a common nail infection, affects physical and emotional well-being. New oral antifungals offer effective treatment, but optimizing regimens is key to cure and preventing relapse.

Area of Science:

  • Dermatology
  • Mycology

Context:

  • Onychomycosis is a prevalent public health issue.
  • Nail disorders are frequently diagnosed as onychomycosis in dermatological settings.
  • The infection significantly impacts patients' quality of life.

Purpose:

  • To review the current understanding of onychomycosis.
  • To discuss treatment strategies for onychomycosis.
  • To highlight factors influencing treatment outcomes.

Summary:

  • Onychomycosis affects a substantial portion of individuals seeking dermatological care for nail conditions.
  • New oral antifungal agents demonstrate high efficacy for fingernail infections, with 60-80% efficacy for toenail onychomycosis.
  • Relapse rates range from 15-20% within two years post-treatment initiation.

Impact:

  • Effective management of onychomycosis requires consideration of pharmacologic and supportive care.
  • Supplemental therapies, including topical or surgical interventions, may enhance treatment outcomes.
  • Addressing onychomycosis is crucial for improving patient physical, functional, and emotional health.

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