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Updated: Aug 1, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Squamous cell carcinoma of the nasal vestibule]
C Klemens1, M Dellian, A Berghaus
1Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Klinikum Grosshadern, Universität München. christine.klemens@med.uni-muenchen.de
Abstract:
The case of a 31-year-old man (smoker) with a progressively enlarging swelling and reddening in the region of the nasal vestibule is discussed. Before he was seen by us, he had been repeatedly treated with antibiotics, but to no avail. A deep excisional biopsy was obtained, and the histopathological work-up revealed a squamous cell carcinoma. Thereupon, complete surgical ablation in healthy tissue was carried out. This case shows that in chronic inflammation of the nasal vestibule that fails to respond to antibiotic treatment differential diagnostic consideration must be given to the possibility of a malignancy.
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