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[Elaboration and validation of an index for preeclampsia diagnosis]
Maria Luisa Peralta Pedrero1, María de los Angeles Guzmán Ibarra, María Antonia Basavilvazo Rodríguez
1Unidad de Medicina Familiar 93 del IMAA. luisaperalta@netscape.net
Objective:
To build a consistent and valid preeclampsia diagnosis index (IDP) for its Spanish acronyms.
Patients And Method:
The study was done in a Gyneco-Obstetrics Hospital and a Family Medicine Unit from March 2000 to February 2001. Fifty items were chosen from the literature, with a design to validate diagnostic tests, which were assessed by family doctors and gyneco-obstetricians in regard to their appearance and content validity. Concurrent criterion validity. Golden standard: Two gyneco-obstetricians diagnosed pre-eclampsia (hypertension and proteinuria). Simultaneously a family doctor (in an independent and blinded way) questioned, examined and recorded laboratory data of 219 preeclamptic patients and 251 non preeclamptic patients.
Results:
Preeclampsia diagnosis index is an additive index with 21 clinical and paraclinical parameters weighted according to their individual diagnostic capacity. It has two parts: The first one with 82% (95%CI 80-84) sensitivity; 93% (95%CI 91-95) specificity; the second one with 86% (95%CI 83-89) sensitivity; 75% (95%CI 65-85) specificity.
Conclusions:
Preeclampsia diagnosis index is easily applied and has immediate results, which makes easier the physician's decisions.
