Related Experiment Video
Updated: Aug 6, 2026

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
Pilot study of trigeminal nerve stimulation (TNS) for epilepsy: a proof-of-concept trial
Christopher M DeGiorgio1, Alan Shewmon, Diane Murray
1UCLA Department of Neurology, David Geffen School of Medicine at UCLA,Los Angeles, CA, USA. cmd@mednet.ucla.edu
Abstract:
The safety and preliminary efficacy of trigeminal nerve stimulation (TNS) for epilepsy was evaluated in a pilot feasibility study of transcutaneous stimulation of the infraorbital and supraorbital branches of the trigeminal nerve. TNS was well tolerated. Four (57%) of seven subjects who completed >or=3 months experienced a >or=50% reduction in seizure frequency. The results of this pilot study support further investigation into the safety and efficacy of TNS for epilepsy.

