NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function

Francisco J Quintana1, Roy Zaltzman, Rafael Fernandez-Montesinos

  • 1Department of Medical Biochemistry and Molecular Biology, The University of Seville School of Medicine, Avda. Sanchez Pizjuan, 4, 41009 Sevilla, Spain.

Summary

The neuroprotective peptide NAP downregulates key inflammatory cytokines in macrophages, suggesting a role in immune regulation alongside its known neuroprotective effects. This peptide, derived from activity-dependent neuroprotective protein (ADNP), impacts immune responses.