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Related Experiment Videos

Simultaneous allergy to vine pollen and grape.

P Mur1, F Feo Brito, B Bartolomé

  • 1Allergy Unit, Hospital Santa Barbara, Puertollano, Ciudad Real, Spain. pilarmurgimeno@saludalia.com

Journal of Investigational Allergology & Clinical Immunology
|August 8, 2006
PubMed
Summary

An 18-year-old student experienced allergic reactions to grapes after pollen sensitization. Cross-reactivity was observed between vine pollen and grape allergens, and among unrelated pollens.

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Area of Science:

  • Allergy and Immunology
  • Plant Science
  • Food Science

Background:

  • Seasonal rhinoconjunctivitis is common, often linked to pollen allergies.
  • Sensitization to multiple pollen types, including vine, grass, olive, and Chenopodiaceae, can occur.
  • Food allergies can develop, sometimes presenting with delayed or complex reactions.

Observation:

  • An 18-year-old student with known pollen sensitivities developed itching, rash, and facial angioedema after consuming grapes.
  • Clinical testing showed positive reactions to both vine pollen and grapes.
  • Specific immunoglobulin E (IgE) antibodies were detected for both vine pollen and grape allergens.

Findings:

  • Immunoblotting and inhibition assays confirmed cross-reactivity between allergenic components of vine pollen and grape fruit.

Related Experiment Videos

  • The study identified cross-reactivity not only between vine pollen and grapes but also among botanically unrelated pollens.
  • This suggests shared allergenic structures or epitopes can trigger reactions across different plant families.

    • Implications:

    • Understanding cross-reactivity is crucial for accurate diagnosis and management of pollen-food allergy syndrome.
    • This case highlights the importance of considering pollen sensitization when evaluating unexplained food reactions.
    • The findings contribute to the broader understanding of allergenicity and cross-reactivity in plant-based foods and pollens.