alphaII-Spectrin interacts with five groups of functionally important proteins in the nucleus

Deepa M Sridharan1, Laura W McMahon, Muriel W Lambert

  • 1Department of Pathology and Laboratory Medicine, UMDNJ, New Jersey Medical School and the Graduate School of Biomedical Sciences, Newark, NJ 07103, USA.

Summary

Nonerythroid alpha-spectrin (alphaSpIISigma(*)) interacts with multiple nuclear proteins involved in DNA repair and chromatin remodeling. Its deficiency in Fanconi anemia (FA) may impact critical cellular pathways.

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