Related Experiment Video
Updated: Aug 6, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Factors underlying suboptimal childhood immunisation
Sarah Tickner1, Patrick J Leman, Alison Woodcock
1Department of Psychology, Royal Holloway, University of London, Egham, Surrey TW20 0EX, UK. s.p.tickner@rhul.ac.uk
Insights
Parents often miss vaccination opportunities for children, impacting coverage for measles, mumps, rubella (MMR) and diphtheria, tetanus, and polio vaccines. Understanding parental decisions and barriers is key to improving childhood immunisation rates.
Area of Science:
- Public Health
- Immunisation Studies
- Paediatric Medicine
Background:
- Childhood immunisation coverage in England shows suboptimal uptake for several key vaccines.
- Missed vaccination opportunities extend beyond measles, mumps, and rubella (MMR), affecting diphtheria, tetanus, and polio (DTP) vaccines.
- Booster immunisation rates lag behind primary course completion for both MMR and DTP vaccines.
Purpose of the Study:
- To explore the reasons behind parents missing vaccination opportunities for childhood immunisations.
- To identify barriers to achieving optimal immunisation coverage in England.
- To inform strategies for improving vaccine uptake based on parental decision-making.
Main Methods:
- Review of international literature on parental vaccine decision-making.
- Analysis of current immunisation coverage data for England.
- Identification of common barriers to childhood vaccination.
Main Results:
- Suboptimal uptake is prevalent for MMR and DTP vaccines, particularly for booster doses.
- International literature highlights various parental concerns and decision-making factors influencing vaccine acceptance.
- Several barriers to immunisation have been identified that require targeted interventions.
Conclusions:
- Addressing parental decision-making and overcoming identified barriers are crucial for enhancing childhood immunisation coverage.
- Improving uptake requires a nuanced understanding of parental perspectives on vaccines like MMR and DTP.
- Strategies to boost immunisation rates must consider both primary and booster vaccination series.
Abstract:
This review considers possible reasons behind parents' missed vaccination opportunities in the context of the latest immunisation coverage rates for England. Suboptimal uptake is not exclusive to measles, mumps and rubella (MMR). A substantial proportion of children also miss diphtheria, tetanus and polio vaccination. For MMR and diphtheria, tetanus and polio, uptake of primary plus booster immunisation is lower than for the primary course alone. Several reasons for suboptimal uptake are identified from the international literature. These provide insights into parental decision-making and potential barriers to immunisation that may need to be addressed in efforts to improve coverage rates.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Vaccinations
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Factors Affecting Illness
For instance, risk factors are connected to illness, disability,...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

