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Updated: Aug 6, 2026
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
Language dominance in mesial temporal lobe epilepsy: a functional transcranial Doppler sonography study of brain
Susanne Knake1, Anja Haag, Guido Pilgramm
1Interdisciplinary Epilepsy Center, Department of Neurology, Philipps University, Rudolf-Bultmann-Strasse 8, 35033 Marburg, Germany. knake@staff.uni-marburg.de
Abstract:
Functional transcranial Doppler sonography was used to study hemispheric language dominance (HLD) in 24 right-handed patients with left temporal lobe epilepsy (TLE) and a structural lesion in the left temporal lobe and in 69 healthy controls. Twenty-five percent of the patients and 4% of controls showed atypical (right or bilateral) HLD. Degree of HLD was not correlated with age, Full Scale IQ, Verbal IQ, spike frequency, seizure frequency, age at seizure onset, or duration of TLE. Atypical HLD appears to be lesion-induced, independent of epilepsy characteristics.
