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Fibrin glue for persistent pneumothorax in an extremely low birth weight infant

Fuat Emre Canpolat1, Murat Yurdakök, Sadik Yurttutan

  • 1Department of Pediatrics, Hacettepe University Ihsan Dogramaci Children's Hospital, Ankara, Turkey.

Indian Pediatrics
|August 8, 2006
PubMed

Insights

Fibrin glue successfully sealed a persistent pneumothorax in an extremely premature infant. This treatment offers a new option for neonates with persistent air leaks unresponsive to conventional ventilation.

Area of Science:

  • Neonatal medicine
  • Pediatric surgery
  • Thoracic medicine

Background:

  • Pleurodesis using fibrin glue is an established treatment for bronchopleural fistulas and persistent air leaks.
  • Conventional treatments, including high-frequency ventilation, may be insufficient for complex air leak cases in neonates.

Observation:

  • A case of an extremely premature infant with a persistent pneumothorax is presented.
  • The pneumothorax had remained unresolved for over a week despite intensive respiratory support with high-frequency ventilation.

Findings:

  • Successful application of fibrin glue pleurodesis was achieved in this extremely premature infant.
  • The fibrin glue effectively sealed the persistent pneumothorax, resolving the air leak.

Implications:

  • Fibrin glue pleurodesis represents a potential therapeutic option for persistent pneumothorax in extremely premature infants.
  • This approach may offer an alternative for neonates with air leaks refractory to standard ventilation strategies.
  • Further research is warranted to evaluate the safety and efficacy of fibrin glue in this vulnerable population.

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