Lumbar total disc replacement using ProDisc II: a prospective study with a 2-year minimum follow-up

Area of Science:

• Spine surgery
• Orthopedic biomechanics

Background:

• Degenerative disc disease (DDD) is a common cause of low back pain.
• Lumbar total disc replacement (TDR) is an evolving surgical option for DDD.

Purpose of the Study:

• To evaluate the clinical and radiographic outcomes of ProDisc II lumbar TDR.
• To identify factors influencing clinical outcomes after TDR.

Main Methods:

• Prospective study of 36 patients undergoing ProDisc II lumbar TDR.
• Minimum 2-year follow-up assessing clinical (VAS, ODI) and radiographic (disc height, ROM) outcomes.
• Statistical analysis to determine factors associated with improved outcomes.

Main Results:

• 94% success rate based on FDA criteria.
• Significant improvements in visual analog scale (VAS) pain scores and Oswestry disability index (ODI).
• Significant increases in disc height and range of motion (ROM) at the operative level.

Conclusions:

• Lumbar TDR with ProDisc II demonstrates excellent short-term clinical and radiographic results for DDD.
• Single-level TDR and higher postoperative ROM are associated with better clinical outcomes.
• Further long-term studies with larger cohorts are warranted.