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The permeability transition pore complex in cancer cell death

C Brenner1, S Grimm

  • 1University of Versailles/St Quentin, CNRS UMR 8159, Versailles, France. catherinebrenner@yahoo.com

Oncogene
|August 8, 2006
PubMed
Summary

The permeability transition pore (PTP) is a key regulator of cell death. Research shows PTP activation by apoptosis signals leads to mitochondrial self-destruction, with specific subunits potentially inhibiting cancer cell death.

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