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Hemodynamic correlates of the third heart sound and systolic time intervals
Sanjiv J Shah1, Andrew D Michaels
1Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, CA, USA.
Insights
New technology enables noninvasive bedside measurement of heart sounds (S3) and systolic time intervals, aiding heart failure diagnosis. This system helps improve patient care by providing objective data previously requiring invasive methods.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Diagnostics
Background:
- Cardiac auscultation and phonocardiography are vital for understanding heart failure pathophysiology.
- Traditional methods for assessing diastolic heart sounds (S3, S4) and systolic time intervals have limitations, including declining auscultation skills and the need for carotid pulse tracings.
- A decline in auscultation skills necessitates improved, objective bedside diagnostic tools for heart failure.
Purpose of the Study:
- To introduce a novel, inexpensive, noninvasive system for automated heart sound detection and systolic time interval measurement.
- To present data on the hemodynamic correlates of the S3 sound and abnormal systolic time intervals using this new technology.
- To establish a foundation for utilizing this system to enhance the understanding and clinical application of S3 and systolic time intervals in heart failure diagnosis and management.
Main Methods:
- Development of a new system for automated, noninvasive detection of heart sounds and measurement of systolic time intervals.
- Utilizing the system to collect data on hemodynamic correlates of the S3 sound and systolic time intervals.
- Analysis of the collected data to establish foundational understanding and test characteristics.
Main Results:
- The new system successfully automates the detection of heart sounds and measurement of systolic time intervals.
- Data were presented on the hemodynamic correlates of the S3 sound and abnormal systolic time intervals.
- The findings support the system's utility in providing objective diagnostic information.
Conclusions:
- The developed system offers a simple, inexpensive, and noninvasive approach to bedside assessment in heart failure.
- This technology can help overcome limitations of traditional auscultation and carotid pulse tracings.
- Further research using this system can refine the understanding of S3 and systolic time intervals, improving heart failure diagnosis and management.
Abstract:
Bedside diagnostic tools remain important in the care of patients with heart failure. Over the past two centuries, cardiac auscultation and phonocardiography have been essential in understanding cardiac pathophysiology and caring for patients with heart disease. Diastolic heart sounds (S3 and S4) and systolic time intervals have been particularly useful in this regard. Unfortunately, auscultation skills have declined considerably, and systolic time intervals have traditionally required carotid pulse tracings. Newer technology allows the automated detection of heart sounds and measurement of systolic time intervals in a simple, inexpensive, noninvasive system. Using the newer system, the authors present data on the hemodynamic correlates of the S3 and abnormal systolic time intervals. These data serve as the foundation for using the system to better understand the test characteristics and pathophysiology of the S3 and systolic time intervals, and help to define their use in improving the bedside diagnosis and management of patients with heart failure.
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