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Monolithic enantiomer-selective stationary phases for capillary electrochromatography
Feng Qin1, Chuanhui Xie, Zhiyuan Yu
1National Chromatographic Research & Analysis Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Journal of Separation Science
|August 10, 2006
Summary
This review covers monolithic materials for enantiomer-selective stationary phases in capillary electrochromatography (CEC). It highlights developments, preparation, characterization, and limitations of various monolithic columns used in CEC.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Monolithic materials are established stationary phases in capillary electrochromatography (CEC).
- Various monolithic types, including particle-fixed, silica-based, polymer-based, and molecularly imprinted, are used for enantioselective separations.
Purpose of the Study:
- To review recent advancements in monolithic enantioselective stationary phases for CEC.
- To discuss the preparation, characterization, and limitations of these phases.
Main Methods:
- Literature review of recent developments in monolithic stationary phases for CEC.
- Focus on preparative procedures and characterization techniques for monolithic columns.
Main Results:
- Summarizes four types of monolithic enantioselective stationary phases: particle-fixed, silica-based, polymer-based, and molecularly imprinted.
- Highlights their preparation and characterization methods.
Conclusions:
- Monolithic materials offer a versatile platform for enantioselective stationary phases in CEC.
- Understanding their preparation and limitations is crucial for further development.
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