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Sensitivity and specificity of new eye check chart for neuro-ophthalmological diseases
Hideki Murai1, Motohiro Kiyosawa2, Manabu Mochizuki1
1Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Purpose:
To determine the sensitivity and specificity of a new Eye Check Chart (ECC) for screening neuro-ophthalmological patients with lesions in the visual pathways.
Methods:
The Humphrey perimeter (HP) with the 30-2 SITA Fast program was used to confirm the visual field defects found in 65 eyes of 35 neuro-ophthalmological patients. Forty eyes had pregeniculate lesions, and 25 eyes had postgeniculate lesions. As controls, 22 eyes of 12 patients without visual field defects were also examined. All subjects were then examined using the eye check chart (ECC) to determine whether comparable visual field defects were detected. The eyes were separated into those in which the ECC findings agreed with the HP findings, and those in which they did not agree. Based on HP results, the sensitivity and specificity of the ECC results were calculated.
Results:
The sensitivity of ECC was 87% in patients with pregeniculate lesions and 80% in patients with postgeniculate lesions. The overall specificity of ECC was 91%.
Conclusion:
This high sensitivity and specificity indicate that ECC can give reliable results in screening neuro-ophthalmological patients for lesions in the visual pathways.
