Efficacy of voriconazole in experimental Cryptococcus neoformans infection
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Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Nikolaos Mavrogiorgos1, Oscar Zaragoza, Arturo Casadevall
1Department of Microbiology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Mycopathologia
|August 10, 2006
Abstract:
Voriconazole is a third generation triazole with improved activity against many fungal pathogens. We examined the efficacy of voriconazole in a murine infection model and evaluated the drug's effect on cellular characteristics and serum polysaccharide levels. The antifungal reduced serum polysaccharide and significantly prolonged the survival of lethally infected animals.

