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Published on: October 27, 2013
Search for the pathogenic fungi in amniotic fluid
D Nowakowska1, J Wilczyński, K Szaflik
1Research Institute Polish Mother's Memorial Hospital, 93-338 Lódź, Rzgowska Str. 281/289.
Wiadomosci Parazytologiczne
|August 11, 2006
Summary
Intra-amniotic Candida infections are rare in preterm rupture of membranes (PROM). Fungal strains were found in women with PROM, but not in amniotic fluid, suggesting routine mycologic diagnostics for these cases.
Area of Science:
- Obstetrics and Gynecology
- Medical Mycology
- Infectious Diseases
Background:
- Intra-amniotic infection by Candida species is an uncommon cause of preterm rupture of membranes (PROM).
- Understanding the role of Candida in amniotic cavity infections is crucial for managing PROM.
Purpose of the Study:
- To investigate mycotic invasion of the amniotic cavity in pregnant women with PROM.
- To compare fungal presence in amniotic fluid between women with PROM and those with intact membranes.
Main Methods:
- A study included 170 pregnant women, divided into two groups: 150 with intact membranes and 20 with PROM.
- Amniotic fluid samples were collected and cultured on Sabouraud's medium.
- Fungal strains were also isolated from the vagina, oral cavity, and rectum of women with PROM.
Main Results:
- No intra-amniotic Candida infections were detected in either the PROM group or the intact membrane group.
- Candida strains were frequently isolated from the vagina, oral cavity, and rectum of women diagnosed with PROM.
- The presence of multifocal Candida infections in women with PROM was observed.
Conclusions:
- Intra-amniotic infection with Candida is not a significant factor in PROM.
- The study recommends mycologic diagnostics for pregnant women with PROM due to the high prevalence of Candida colonization.
- Early detection and management of Candida colonization may be important in cases of PROM.
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