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Published on: June 26, 2018
Use of proteomics in analysis of autoimmune diseases
1Department of Bioregulation and Proteomics, Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan.
Abstract:
Autoimmune diseases are common by diseases characterized by disorders of immune responses and autoimmune impairment involving multiple tissues, organs and systems. The autoantigens (Ags)/autoantibodies (Abs) are not only hallmarks but also involved in pathogenesis of autoimmune diseases. In recent years, proteomics technologies have been used and demonstrated effective in searching new Ags/Abs as well as disease biomarkers in autoimmune diseases.