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Related Experiment Videos

Practical management of medication-overuse headache.

Koen Paemeleire1, Luc Crevits, Peter J Goadsby

  • 1Department of Neurology, Ghent University Hospital, Belgium. Koen.Paemeleire@Ugent.be

Acta Neurologica Belgica
|August 11, 2006
PubMed
Summary

Medication-overuse headache (MOH) is common in chronic daily headache patients. Effective treatment strategies exist, though clinical trials are limited, and this review details current approaches.

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Area of Science:

  • Neurology
  • Clinical Pharmacology

Background:

  • Medication-overuse headache (MOH) is highly prevalent in patients experiencing chronic daily headache.
  • MOH could be the third most common headache disorder globally if all medication overuse leads to it.

Purpose of the Study:

  • To review current data on MOH, including its clinical features.
  • To summarize drugs and strategies for withdrawal from overused medications.
  • To describe practical in-patient and out-patient withdrawal procedures.

Main Methods:

  • Literature review of available data on medication-overuse headache.
  • Synthesis of clinical features, pharmacological treatments, and withdrawal strategies.
  • Description of expert-based in-patient and out-patient withdrawal protocols.

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Main Results:

  • Medication-overuse is a frequent issue in chronic headache sufferers.
  • Despite a lack of extensive clinical trials, headache centers report success in treating MOH.
  • Various drugs and structured withdrawal approaches are utilized.

Conclusions:

  • MOH is a significant and common headache disorder.
  • Expert-led withdrawal programs offer effective treatment options for MOH.
  • Further research, including randomized controlled trials, is needed to validate specific treatments.