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[Irritable bowel syndrome in children]

Yoshiko Nakayama1, Akira Horiuchi

  • 1Department of Pediatrics, Showa Inan General Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|August 11, 2006
PubMed

Insights

Irritable bowel syndrome (IBS) in children and adolescents is best managed using a biopsychosocial approach. Further research is needed for new medications targeting gut-brain pathways to improve symptom relief and daily functioning.

Area of Science:

  • Gastroenterology
  • Pediatrics
  • Neurogastroenterology

Context:

  • Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder in pediatric populations.
  • Advances in Rome diagnostic criteria and understanding of brain-gut pathways have reshaped IBS management.
  • The biopsychosocial model is crucial for evaluating and treating children and adolescents with IBS.

Purpose:

  • To summarize current understanding and management strategies for IBS in children and adolescents.
  • To highlight the importance of the biopsychosocial model in pediatric IBS care.
  • To identify areas for future research, particularly in pharmacologic interventions.

Summary:

  • Current management of pediatric IBS emphasizes a biopsychosocial framework to address symptoms and functional disability.
  • The enteric nervous system's sensorimotor function is a key area for potential therapeutic targets.
  • Developing novel drugs to modulate these pathways is essential for improving treatment outcomes.

Impact:

  • Improved clinical evaluation and treatment protocols for pediatric IBS.
  • Potential for new drug development targeting specific pathophysiological mechanisms in IBS.
  • Enhanced quality of life for children and adolescents suffering from IBS and associated disabilities.

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