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[Irritable bowel syndrome in children]
Yoshiko Nakayama1, Akira Horiuchi
1Department of Pediatrics, Showa Inan General Hospital.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|August 11, 2006
Summary
Irritable bowel syndrome (IBS) in children and adolescents is best managed using a biopsychosocial approach. Further research is needed for new medications targeting gut-brain pathways to improve symptom relief and daily functioning.
Area of Science:
- Gastroenterology
- Pediatrics
- Neurogastroenterology
Context:
- Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder in pediatric populations.
- Advances in Rome diagnostic criteria and understanding of brain-gut pathways have reshaped IBS management.
- The biopsychosocial model is crucial for evaluating and treating children and adolescents with IBS.
Purpose:
- To summarize current understanding and management strategies for IBS in children and adolescents.
- To highlight the importance of the biopsychosocial model in pediatric IBS care.
- To identify areas for future research, particularly in pharmacologic interventions.
Summary:
- Current management of pediatric IBS emphasizes a biopsychosocial framework to address symptoms and functional disability.
- The enteric nervous system's sensorimotor function is a key area for potential therapeutic targets.
- Developing novel drugs to modulate these pathways is essential for improving treatment outcomes.
Impact:
- Improved clinical evaluation and treatment protocols for pediatric IBS.
- Potential for new drug development targeting specific pathophysiological mechanisms in IBS.
- Enhanced quality of life for children and adolescents suffering from IBS and associated disabilities.
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