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Published on: August 7, 2017
Risk factors for reduced lung function in Australian Aboriginal children
Ingrid K Bucens1, Alison Reid, Susan M Sayers
1Health Alliance International, Dili, East Timor. ingbucens@hotmail.com
Insights
Childhood environmental factors significantly impact lung function in Aboriginal children. Factors like non-urban residence and respiratory hospitalizations negatively affected lung health, more so than perinatal issues.
Area of Science:
- Pediatric Pulmonology
- Environmental Health
- Indigenous Health Research
Background:
- Lung function is crucial for overall child health and development.
- Understanding environmental influences on respiratory health in Indigenous populations is vital.
Purpose of the Study:
- To investigate the impact of perinatal and childhood exposures on lung function in Australian Aboriginal children.
- To identify key environmental determinants of respiratory health in this cohort.
Main Methods:
- Cross-sectional study of 547 Aboriginal children (8-14 years) in the Northern Territory.
- Utilized physical examination, spirometry, and hospital record review.
- Multiple regression analysis adjusted for age, sex, and height to assess exposure effects on lung function (FEV1, FVC, FEF25-75).
Main Results:
- Non-urban residence, current cough, and respiratory disease hospitalizations were associated with significantly reduced lung function.
- Neonatal lung disease was the only significant perinatal factor affecting lung function.
- Children with non-Aboriginal ancestry exhibited better lung function.
Conclusions:
- Childhood environmental factors play a more significant role than perinatal factors in determining lung function for Northern Territory Aboriginal children.
- Interventions targeting childhood environmental exposures may improve respiratory health outcomes.
Aim:
To determine the influence of perinatal and childhood exposures on lung function in a cohort of Australian Aboriginal children.
Methods:
This was a cross-sectional study of 547 Northern Territory Aboriginal children, aged 8-14 years, belonging to a birth cohort. Assessment included physical examination and spirometry as well as retrospective review of centralised hospital records. The effect of select perinatal and childhood exposures on lung function outcomes (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and forced expiratory flow between 25 and 75 s (FEF25-75)) adjusted for age, sex, height and other measures of size was examined using multiple regression.
Results:
Non-urban residence (FEV1 -5% (95% confidence interval, CI 0.91-0.99), FVC -9% (95% CI 0.87-0.95)), current cough (FEV1 -6% (95% CI 0.91-0.97), FVC -4% (95% CI 0.93-0.97), FEF25-75 -8% (95% CI 0.86-0.98)) and hospitalisations for respiratory disease (FEV1 -10% (95% CI 0.86-0.95), FEF25-75 -12% (95% CI 0.70-0.87)) all had significant negative effects on adjusted lung function measures. Children with a non-Aboriginal ancestor had significantly better lung function. No perinatal exposure other than neonatal lung disease had any significant effect on adjusted lung function.
Conclusions:
For Northern Territory Aboriginal children factors related to the childhood environment are more important than perinatal factors in determining childhood lung function.
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