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Updated: Aug 6, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
Myelodysplastic syndrome transformed into Acute Lymphoblastic Leukaemia (FAB:L3)
1Department of Clinical Laboratory Sciences, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia. zainina@medic.upm.edu.my
Abstract:
Myelodysplastic syndrome (MDS) is recognized as a preleukaemic disorder with a variable risk of transformation to acute myeloid leukaemia. Usually the blast cells in leukaemia are transformed after MDS displays a myeloid phenotype. Even though lymphoid progression had been reported previously, most displayed myeloid-lymphoid hybrid or early B phenotype. We report a case of an elderly man who had MDS transformed into Acute Lymphoblastic Leukaemia (ALL:L3) which is a rare lymphoid transformation.
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