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Updated: Aug 6, 2026

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
Published on: December 1, 2023
[Effects of puberty on glucose-lipid balance during exercise in the obese child]
Gautier Zunquin1, Denis Theunynck, Bruno Sesboüé
1Laboratoire de Physiologie Digestive et Nutritionnelle, Centre Hospitalier Universitaire (CHU) de Caen, France.
Abstract:
The aim of the present study was to investigate effect of puberty on substrate oxidation rates using a graded exercise test to exhaustion. Two groups of obese adolescent males (34 prepubertal: body mass index (BMI) = 25,94 +/- 2,63; Z-score = 4,43 +/- 1,83; and 26 postpubertal: BMI = 31,14 +/- 4,88; Z-score = 5,264 +/- 1,76) performed an exercise test on a cycle ergometer. The test consisted in a series of graded exercises on a cycle ergometer. Stage duration was 3 min 30 s. Fat and carbohydrate rates were calculated during the last 30 s of each stage using stoichiometric equations, and this permitted us to calculate substrate oxidation according to exercise intensity. Lipid oxidation rates are significantly higher in the postpubertal group. When the fat oxidation rates are reported relative to fat free mass, fat oxidation rates are higher in the prepubertal group. Puberty decreases significantly the capacity of fat free mass to oxidize fat for a same level of exercise.
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