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Responsiveness of the coronary revascularisation outcome questionnaire compared with the SF-36 and Seattle Angina
Sara Schroter1, Donna L Lamping
1Health Services Research Unit, London School of Hygiene & Tropical Medicine, London, UK. sschroter@bmj.com
Insights
The Coronary Revascularisation Outcome Questionnaire (CROQ) shows comparable responsiveness to the Seattle Angina Questionnaire (SAQ) and superior responsiveness to the SF-36 in cardiac surgery patients. This finding aids in selecting appropriate patient-reported outcome measures.
Area of Science:
- Cardiology
- Health Outcomes Research
- Medical Instrumentation
Background:
- Assessing patient outcomes after coronary revascularisation is crucial.
- Validated instruments are essential for measuring treatment effectiveness.
- Comparing responsiveness of different questionnaires aids clinical decision-making.
Purpose of the Study:
- To compare the responsiveness of the Coronary Revascularisation Outcome Questionnaire (CROQ) against the Seattle Angina Questionnaire (SAQ) and the SF-36.
- To evaluate these instruments in patients undergoing coronary bypass surgery (CABG) and percutaneous transluminal coronary angioplasty (PTCA).
Main Methods:
- A randomized comparison of three instruments: CROQ, SAQ, and SF-36.
- 199 patients (127 CABG, 72 PTCA) completed questionnaires before and 3 months after revascularisation.
- Effect sizes and standardized response means were calculated and compared using bootstrap estimation.
Main Results:
- The CROQ demonstrated greater change in psychosocial functioning than the SF-36 for CABG patients.
- For PTCA patients, the CROQ showed greater symptom change than the SAQ, while the SAQ was more responsive for physical functioning.
- The CROQ was found to be as responsive as the SAQ and more responsive than the SF-36 overall.
Conclusions:
- The CROQ is a responsive instrument for evaluating outcomes in patients after coronary revascularisation.
- The CROQ offers a valuable alternative to the SAQ and SF-36 for assessing patient-reported outcomes in cardiology.
- Findings support the use of the CROQ in clinical trials and practice for CABG and PTCA patients.
Abstract:
We describe a comparison of the responsiveness of three validated instruments when used with patients undergoing coronary bypass surgery (CABG) and angioplasty (PTCA). Patients were randomly selected to receive the Coronary Revascularisation Outcome Questionnaire (CROQ), and either the Seattle Angina Questionnaire (SAQ), or the SF-36 before and 3 months after coronary revascularisation. At total of 199 patients (127 CABG, 72 PTCA) completed the CROQ; 55/72 CABG and 34/38 PTCA patients also completed the SAQ or SF-36, respectively. Effect sizes and standardised response means were calculated as change over the 3-month period for scales measuring similar constructs on each instrument. We used bootstrap estimation to derive 95% confidence intervals for differences in the responsiveness indices. For CABG, the CROQ demonstrated significantly greater change in psychosocial functioning than the SF-36, but less than the SAQ. For PTCA, the CROQ showed greater change for symptoms than the SAQ, but the SAQ was more responsive in terms of physical functioning; and the CROQ showed significantly greater change than the SF-36 for psychosocial functioning. There were no other significant differences between similar scales on the three instruments. In conclusion, the CROQ was as responsive as the disease-specific SAQ and more responsive than the generic SF-36.
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