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Published on: April 17, 2020
[Experimental study of preventing postoperative stenosis by modifying artificial esophagus in dogs]
Lan-Jun Zhang1, Tie-Hua Rong, Guo-Liang Xu
1State Key Laboratory of Oncology in Southern China, Department of Thoracic Surgery, Cancer Center, Sun Yat-sen University, Guangzhou 510060, China. lj.zhang@medmail.com.cn
Objective:
To observe the effect of the modified artificial esophagus on postoperative stenosis in dogs.
Methods:
The models of defected esophagus were established in dogs. The double-layered membrane tube (modifying type) was implanted in the test group (n = 10) and the esophageal stent was further inserted when the stenosis occurred. The single pattern tube (original type) was transplanted to the control group (n = 30). The dilation treatment was performed to relieve the postoperative stenosis; alternatively, the esophageal stent was implanted in the unsuccessful dogs.
Results:
The average artificial esophagus removal time was 19.10 days in the test group, which was significantly lower than 39.07 days in the control group (t = 15.6, P = 0.000). No obstruction after removal was observed in the experimental group. The incidence of postoperative stenosis had no significant difference between these two groups.
Conclusion:
The double-layered membrane tube can make the tube removal safer by shortening the removal time.
