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Updated: Aug 6, 2026
07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Gastric bypass in a factor V deficient patient
Syed Husain1, Naveen Ballem, Howard L Beaton
1Department of Surgery, Harlem Hospital Center, New York, NY 10037, USA. sh2144@columbia.edu
Obesity Surgery
|August 12, 2006
Summary
Factor V deficiency, a rare bleeding disorder, presents surgical challenges. This case demonstrates successful peri-operative management with fresh frozen plasma during Roux-en-Y gastric bypass, a first for bariatric surgery.
Area of Science:
- Hematology
- Surgical Oncology
- Gastroenterology
Background:
- Factor V deficiency is a rare inherited bleeding disorder.
- Peri-operative management of Factor V deficiency requires careful consideration due to bleeding risks.
- Optimal surgical strategies for patients with Factor V deficiency are not well-established.
Observation:
- A patient with Factor V deficiency underwent a Roux-en-Y gastric bypass.
- The peri-operative period required meticulous attention to hemostasis.
Findings:
- Successful surgical intervention was achieved using peri-operative fresh frozen plasma infusion.
- This represents the first reported instance of bariatric surgery in an individual with Factor V deficiency.
Implications:
- This case highlights the feasibility of bariatric surgery in select Factor V deficient patients.
- Peri-operative fresh frozen plasma administration is a viable strategy for managing Factor V deficiency during complex surgeries.
- Further research is warranted to establish definitive guidelines for managing Factor V deficiency in bariatric surgery.
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