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Basophil releasability in human hydatidosis
A Aceti1, D Celestino, M Caferro
1Istituto di Clinica delle Malattie Tropicali e Infettive, Università La Sapienza, Roma, Italia.
International Archives of Allergy and Applied Immunology
|January 1, 1990
Abstract:
We studied immunoglobulin E (IgE)- and non-IgE-mediated releasability in basophils from 31 patients with hydatidosis. Histamine release to non-IgE-dependent stimuli did not differ significantly between normal individuals and patients with hydatidosis. On the contrary, an increased histamine liberation was obtained by challenging basophils from hydatid patients with anti-human IgE. It is concluded that Echinococcus granulosus infection induces an enhanced sensitivity of basophils to IgE-dependent stimuli.