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Two new bioactive sesquiterpenes from the soft coral Sinularia sp
Guang-Wen Zhang1, Xiang-Quan Ma, Jing-Yu Su
1School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China.
Natural Product Research
|August 12, 2006
Abstract:
Two new sesquiterpenes, 1S*, 4R*, 5S*, 6R*, 7S*, 10S*-1(5), 6(7)-diepoxy-4-guaiol (1) and 1S*, 4S*, 5S*, 10R*-4,10-guaianediol (2) have been isolated from the ethyl acetate soluble portion of the soft coral Sinularia sp., and their stereostructure were determined by spectroscopic methods and by X-ray single crystal analysis. Both compounds showed antioxidant and cytotoxic activities.
