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Published on: February 17, 2022
Boronated thymidine analogues for boron neutron capture therapy
B T S Thirumamagal1, Jayaseharan Johnsamuel, Guirec Y Cosquer
1College of Pharmacy, The Ohio State University, Columbus, Ohio 43120, USA.
Nucleosides, Nucleotides & Nucleic Acids
|August 12, 2006
Abstract:
Concise synthetic methods for synthesizing 3-carboranyl thymidine analogues (3CTAs) modified with cyclic and acyclic alcohols have been developed. The synthesis of these potential boron neutron capture therapy (BNCT) agents and their preliminary biological evaluation is described.

