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Updated: Aug 6, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Discussing quality-of-life issues with a patient newly diagnosed with prostate cancer
John L Gore1, David F Penson, Mark S Litwin
1Department of Urology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA. jgore@mednet.ucla.edu
Background:
A 66-year-old man with hypertension, hyperlipidemia, and benign prostatic hyperplasia presented for evaluation of an elevated PSA level of 6.2 ng/ml.
Investigations:
Transrectal ultrasound-guided 12-core prostate needle biopsy.
Diagnosis:
Clinically localized, clinical stage T1c adenocarcinoma of the prostate.
Management:
Following a full discussion of the risks and benefits of his treatment options, including quality-of-life sequelae, the patient opted for radical prostatectomy.
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